Careers at VGXI

If you are driven by innovation, fueled by scientific curiosity, and committed to making a positive impact on the global pharmaceutical community, you’ve come to the right place. We are always looking for quality-minded, team-oriented individuals who share our dedication to excellence. At VGXI, we’ve cultivated a workplace that people genuinely enjoy being a part of, and we take immense pride in the role they play in shaping our success story. We embrace a culture of quality in our products and in our people. Explore the possibilities, unlock your potential, and contribute to the future of Plasmid DNA manufacturing and precision medicine with VGXI.

Business Development Manager

Responsible for professional representation and promotion of the company’s services to prospective and existing clients within the established territory or otherwise as assigned, with the primary goal to drive new sales and increase market share.

 

Essential duties and responsibilities include the following. Other duties may be assigned.

  • Identify, engage, and develop new business opportunities and business relationships.
  • Drive deal progression to contract execution in support of sales targets and revenue objectives.
  • Confidently and proactively represent the company, including at various conferences, meetings, and industry events.
  • Nurture assigned territory, promoting sales of the company’s services and soliciting RFIs/RFPs.
  • Prepare documentation and present company services in the form of estimates, proposals, and solution presentation to prospective customers.
  • Establish cross-functional relationships and work collaboratively with internal departments to support proposal generation and deal progression.
  • Initiate and coordinate off-site and on-site customer visits, working closely with internal departments to align resources as applicable.
  • Maintain up-to-date records for contacts, deals and all sales activities in the CRM.
  • Work closely with customers to ensure high levels of customer satisfaction at all stages.
  • Provide regular feedback to sales management on ongoing voice of customer and competitive landscape.
  • Develop and maintain broad understanding of the company services, capabilities, technology and relevant industry markets.

 

EDUCATION and/or EXPERIENCE

  • BS or MS with focus in biotechnology or biology and 2+ years’ industry experience in sales, business development, or similar client facing role.
  • Proficient in Microsoft Office applications including Word, Excel, and PowerPoint.
  • Experience with CRM platforms.
  • Ability to work independently, prioritize, and complete tasks on time.
  • Strong organizational skills and attention to detail.
  • Excellent communication skills to work effective with clients and other team members.

Manufacturing Supervisor

Responsible for coordinating effort within the Manufacturing Team to manufacture revolutionary clinical and commercial nucleic acid-based pharmaceuticals by interfacing with manual and automated production systems and controls in cGMP manufacturing environment while maintaining areas in a state of compliance with internal quality systems. Ensure personnel are trained and follow standard operating procedures to safely operate production equipment for manufacturing operations. Maintains records, processes, and clean room environments to comply with regulatory requirements utilizing current Good Manufacturing Practices (cGMP) and Standard Operating Procedures (SOP). Identify, evaluate, test, and implement new technologies for process improvements.  Responsible for the implementation of current Good Manufacturing Practices (cGMP) in production areas. Responsible for proficiency in assigned functional areas. Understands and applies biological, chemical, and mechanical principles and techniques.

 

ESSENTIAL DUTIES AND RESPONSIBILITIES include the following. Other duties may be assigned.

  • Manufacture plasmid DNA conforming to GMP guidelines and VGXI SOPs.
  • Executes production plan by assigning personnel, accomplishing work results, establishing priorities, monitoring progress, and reporting results of the processing flow to Manufacturing Management.
  • Qualified in all processes involved in the manufacture of plasmid DNA and able to train and explain technical aspects of manufacturing processes to junior staff.
  • Specify and procure appropriate equipment as needed.
  • Install, commission and troubleshoot equipment as needed.
  • Interface with other operational departments to facilitate scale-up and technology transfer to meet growing demands.
  • Write and review Standard Operating Procedures (SOP) and production batch records.
  • Implement new equipment and processes for the manufacture of plasmid DNA.
  • Mentor junior staff and support team growth through the supervision of assigned projects.
  • Ensure continuous improvement initiatives and foster innovation within the Manufacturing staff.

 

EDUCATION and/or EXPERIENCE

Bachelor’s Degree (B.S.) or equivalent; or three to five years related experience and/or training; or equivalent combination of education and experience.

Quality Control Analytical Chemist

The Analytical Chemist is responsible for new assay development, method transfers, assay qualifications and validations. It is also the responsibility of this position to troubleshoot any problems that may arise and to be up-to-date on all methods applicable for QC use. QC Analytical Chemist will also participate in testing of products manufactured at VGXI.

 

ESSENTIAL DUTIES AND RESPONSIBILITIES include the following. Other duties may be assigned.

  • Knowledge and experience in developing and validating methods utilizing liquid chromatography (HPLC/UPLC, CGE and LCMS) is required.
  • Experiments may range from analyses using HPLC, CGE, Spectrophotometer, ELISA Assays, Gel Electrophoresis, and other instrumental methods to non-instrumental methods (wet chemical methods).
  • Knowledge of departmental procedures and policies.
  • Train junior staff on assays and GMP Practices.
  • Able to work in a fast-paced environment.
  • Day-to-day operations of the Quality Control Laboratory including testing, documentation and laboratory maintenance.
  • Support performance targets for the laboratory, and monitor actual performance against targets, taking appropriate and timely CAPA where applicable.
  • Support awareness and achievement of all regulations.
  • Provide technical support to the manufacturing team regarding issues which arise and are detected in the laboratory and also for trials which are performed as part of Root Cause investigation.
  • Support all Process and Equipment Validation projects where laboratory services are required.

 

EDUCATION and/or EXPERIENCE

Bachelor’s Degree (B.S.) or equivalent; or five to seven years related experience and/or training; or equivalent combination of education and experience.

Quality Control Technician

The Quality Control Technician is responsible for in-process, release and stability testing of products manufactured at VGXI. Responsibilities also include raw material testing. Set-up, organization, and day-to-day operations of a Quality Control Lab are also required.

 

ESSENTIAL DUTIES AND RESPONSIBILITIES include the following. Other duties may be assigned.

  • Experiments may range from analyses using Spectrophotometer, ELISA Assays, Gel Electrophoresis, qPCR, HPLC, CGE and other instrumental methods to non-instrumental methods (wet chemical methods).
  • Knowledge of departmental procedures and policies.
  • Able to work in a fast-paced GMP environment.
  • Day-to-day operations of the Quality Control Laboratory including testing, documentation and laboratory maintenance.
  • Support performance targets for the laboratory, and monitor actual performance against targets, taking appropriate and timely CAPA where applicable.
  • Support awareness and achievement of all regulations.
  • Provide technical support to the manufacturing team regarding issues which arise and are detected in the laboratory and also for trials which are performed as part of Root Cause investigation.
  • Support all Process and Equipment Validation projects where laboratory services are required.

 

EDUCATION AND/OR EXPERIENCE

Bachelor’s Degree (B.S.) or equivalent; or three to five years related experience and/or training; or equivalent combination of education and experience

Environmental Monitoring Technician

The primary responsibility of the Environmental Monitoring Technician is to perform all EM monitoring and related testing; water sampling, gas sampling and testing. Set-up, organization, and day-to-day operations of a Quality Control Lab are also required.

 

ESSENTIAL DUTIES AND RESPONSIBILITIES include the following. Other duties may be assigned.

  • Monitoring activities include but not limited to Non-viable air-borne, viable
  • Sampling and testing of WPU, WFI, process gases, Microbial testing, TOC and other wet chemical testings.
  • Able to work in a fast-paced GMP environment using aseptic techniques.
  • Working knowledge of trending software
  • Knowledge of departmental procedures and policies.
  • Day-to-day operations of the Quality Control Laboratory including testing, documentation and laboratory maintenance.
  • Support performance targets for the laboratory, and monitor actual performance against targets, taking appropriate and timely CAPA where applicable.
  • Support awareness and achievement of all regulations.
  • Provide technical support to the manufacturing team regarding issues which arise and are detected in the laboratory and also for trials which are performed as part of Root Cause investigation.
  • Support all Process and Equipment Validation projects where laboratory services are required.

 

EDUCATION AND/OR EXPERIENCE

Bachelor’s Degree (B.S.) or equivalent and two to five years related experience and/or training; or equivalent combination of education and experience. Preferred experience with execution of cleaning validations and of EMPQ.

Upstream & Downstream Manufacturing Process Technician

Responsible for manufacturing revolutionary clinical and commercial nucleic acid-based pharmaceuticals by interfacing with manual and automated production systems and controls in cGMP manufacturing environment while maintaining areas in a state of compliance with internal quality systems. Follows standard operating procedures to operate production equipment for upstream/downstream operations. Maintains records, process, and clean room environment to comply with regulatory requirements utilizing current Good Manufacturing Practices (cGMP) and Standard Operating Procedures (SOP). Responsible for proficiency in assigned functional area: Upstream/Downstream Manufacturing. Understands and applies biological, chemical, and mechanical principles and techniques.

 

ESSENTIAL DUTIES AND RESPONSIBILITIES include the following. Other duties may be assigned.

  • Manufacture plasmid DNA conforming to GMP guidelines and VGXI SOPs.
  • Upstream: Follow production records or SOPs and accurately document work to conduct cell banking, fermentation, and lysis processes for plasmid DNA manufacture                                                                                                                                                                                                                      or
  • Downstream: Follow production records or SOPs and accurately document work to conduct chromatography, filtration, aseptic processing, and product formulation and filling for plasmid DNA manufacture.
  • Perform work following aseptic processing guidelines as appropriate.
  • Prepare solutions required for the production process (media and buffer make-up).
  • Clean, assemble, and sterilize equipment for production by operating glass washers and autoclaves.
  • Write or Revise Standard operating procedures.
  • Install, commission and troubleshoot equipment as needed.
  • Responsible for documentation and maintenance of equipment, such as: documenting new equipment and equipment changes, conducting and documenting PM as required, ensuring proper documentation of equipment repair, etc.
  • Perform daily cleaning and sanitization of Production Areas.

 

EDUCATION and/or EXPERIENCE

Bachelor’s or Associate’s degree or equivalent from college or technical school; or one to three years related experience and/or training; or equivalent combination of education and experience.

MSAT Process Engineer

The Process Engineer works as part of the Process Engineering Section of the MSAT Team to translate technical requirements into tangible infrastructure and scalable processes. The PE section relies on close collaboration with PD, MFG, Facilities, OT, and Quality to bring theoretical optimizations into reality. The Process Engineer will analyze existing processes, identify areas for improvement and implement creative solutions to enhance operational performance. The PE section owns engineering change management as it relates to manufacturing equipment and processes.

 

ESSENTIAL DUTIES AND RESPONSIBILITIES include the following. Other duties may be assigned.

  • Facilitate technology transfer from PD to MFG
  • Identify and implement process improvements to increase compliance, reduce costs, minimize waste and increase efficiency.
  • Collaborating with cross-functional teams to ensure smooth integration of new processes, technologies and equipment.
  • Monitor and analyze process data, identify trends, and propose solutions for process improvements.
  • Collaborate with process development, manufacturing and quality assurance teams to develop and implement standard operating procedures (SOPs) and production documents.
  • Provide technical support and troubleshooting expertise to resolve process-related issues
  • Support process validation activities, including protocol development, execution and documentation, ensuring compliance with regulatory requirements.
  • Responsible for writing and reviewing documents involved in technology transfer of production processes into GMP production in collaboration with VGXI’s client, PD, MFG, QC and QA.

 

EDUCATION and/or EXPERIENCE

Bachelor’s degree in engineering or biology, biotechnology, molecular biology, biochemistry, chemistry, bioengineering or closely related field with four or more years in GMP Manufacturing, Process Development, Process Engineering, MSAT or equivalent combination of education and experience.

Process Development Technician

Conduct research scale production of plasmid DNA on an ongoing basis. Perform and document routine maintenance on PD equipment. Assist in the execution and analysis of data for the purpose of fermentation and purification process development. Assist the analysis of samples from cGMP seed banking, fermentation and purification processes. Assist experiments to evaluate new technologies as designed and supervised by senior team members. Maintain a clean and organized laboratory environment.

 

ESSENTIAL DUTIES AND RESPONSIBILITIES include the following. Other duties may be assigned.

  • Follow batch records or SOPs to conduct cell banking, fermentation and purification processes
    for plasmid DNA manufacture at research or GLP scale.
  • Conduct miniprep, concentration and gel analysis to in-process samples of research and cGMP
    productions.
  • Responsible for documentation and maintenance of PD equipment, such as: documenting new
    equipment and equipment changes, changing temperature charts, conducting and
    documenting PM for certain PD equipment, etc.
  • Execute or assist fermentation experiments designed by senior team members to optimize
    fermentation process.
  • Execute or assist in purification experiments designed by senior team members to optimize
    plasmid purification process.
  • Execute or assist in experiments designed by senior team members to evaluate new
    technologies.
  • Perform and record Daily and Weekly cleaning of PD area.
  • Clean and sanitize process-related glassware and equipment.

 

EDUCATION and/or EXPERIENCE

Bachelor’s or Associate’s degree or equivalent from college or technical school; or one to three years related experience and/or training; or equivalent combination of education and experience

Sr. Program Manager

Oversees all aspects of client-facing programs and coordinates between management and internal and external stakeholders. Develops detailed work plans, schedules, project estimates, resource plans, and status reports. Assesses program risks and implements mitigation strategies to ensure success from initiation through program completion.

 

ESSENTIAL DUTIES AND RESPONSIBILITIES include the following. Other duties may be assigned.

  • Demonstrate effective management of client facing programs to ensure adherence with timelines, manage risks, and support successful completion of short and long term goals
  •  Provide the highest level of customer-focused support to nurture and strengthen client accounts, build successful relationships with key client stakeholders, and drive the company’s net promoter score (NPS)
  • Represent the organization in customer facing communications, including navigating conflicts within a collaborative and partnership approach
  • Coordinate with the commercial team to support the definition of project scope, objectives, and timelines, involving relevant stakeholders to ensure resource and timeline feasibility
  • Ensure effective tracking tools and processes are in place and provide regular reports to leadership regarding revenue goals, budgets, resource allocations, and other established metrics or KPIs
  • Maintain and drive the company’s rolling revenue forecast to ensure accuracy and alignment with company goals and internal KPIs
  • Lead weekly pipeline-capacity review meetings with relevant internal stakeholders to align sales pipeline and sales forecasts with production capacity and procurement activities
  • Organize client-facing program core teams, kickoff meetings, and regular to support seamless onboarding and coordination across all levels of the organization for client programs
  • Coordinate regular meetings for active programs and ensure effective tracking and communication of progress, outcomes, actions, and key deadlines
  • Conduct client-facing program summary meetings and internal post-program review meetings to evaluate timeline adherence, reprocessing rates, key production metrics, lessons learned and to solicit feedback
  • Maintain in-depth knowledge of the company’s services and coordinate with the sales and business development team to support changes in scope and promote new business opportunities
  • Drive continuous improvement in all aspects of the company’s program management activities based on industry best practices
  • Perform other related duties as assigned

EDUCATION and/or EXPERIENCE

Bachelor’s or associate degree in a relevant field and 6+ years of relevant project management
experience

Benefits

At VGXI, we recognize that our employees are at the heart of our success, and we offer exceptional benefits that reflect our commitment to their well-being. Our comprehensive offerings include a range of quality benefits, available to our employees from day one (no waiting period). Benefits include:

  • Medical
  • Dental
  • Vision
  • Life Insurance
  • Short-Term and Long-Term Disability
  • 401K Plan
  • Flexible Spending Account
  • Tuition Reimbursement
  • Paid Time Off Including Holidays, Vacation and Sick/Personal Leave

Diversity, Equity and Inclusion

At VGXI, we are committed to recognizing and valuing you. Our diverse backgrounds, perspectives, and contributions fuel innovation and allow us to success both as individuals and as a team. We have established and embrace a culture of acceptance and inclusion with equity in recruiting, hiring, developing, and investing in talented people. Our commitment to these principles supports a diverse workforce and empowers us to achieve our mission of leading the industry in producing the next generation of therapeutics to improve patients’ lives.