With original operations based in The Woodlands, TX, industry recognized plasmid DNA contract manufacturer VGXI, Inc. celebrated the official Grand Opening of its new headquarters and expanded manufacturing facility in Conroe, TX. VGXI, Inc., a specialized contract developer and manufacturer (CDMO) of nucleic acid biopharmaceuticals including gene therapies, DNA vaccines, and RNA… Read More »
According to Science Daily a research group at Karolinska Institutet has developed a DNA-vaccine against DLL4 (a protein which has recently been identified as an important component in regulating the formation of new blood vessels) and the blood vessel tip cells. They have shown that the vaccination against DLL4 causes an immunological… Read More »
A recent article distributed by the University of Florida describes their recent development of a gene therapy that could help both people and animals with osteoarthritis. Osteoarthritis, the most common type of arthritis, is a debilitating condition that causes inflammation and deterioration of the joints. Mostly the condition affects large weight-bearing joints… Read More »
As we’re quickly approaching the end of October and Breast Cancer Awareness Month, I have recently started following Cancerconnect.com on Twitter (@cancerconnect). I have found a lot of the information they have posted with regard to breast cancer to be very interesting and informational about various topics. I wanted to take the… Read More »
According to a recent press release, researchers at Ohio State University have discovered how to inject a precise dose of a gene therapy agent directly into a single living cell without the use of a needle. This technique, “nanochannel electroporation,” or NEP uses electricity to propel pieces of therapeutic biomolecules through a… Read More »
I recently read an interesting article from Fiercebiotech.com that highlights 10 late-stage cancer drugs that “represent the advancement of relatively new methods of attacking cancer, including “armed antibodies” and cancer-killing viruses.” 1. Carfilzomib – multiple myeloma 2. Crizotinib (PF-02341066) – lung cancer 3. GDC-0449 (vismodegib) – basal cell carcinoma 4. OncoVex – advanced melanoma… Read More »
This past week at the 5th Vaccine and ISV Annual Global Congress in Seattle, Coridon Pty Ltd and their major investor Allied Healthcare Group, presented results from their pioneering DNA vaccine against herpes simplex virus 2. The astounding results of their pre-clinical efficacy study showed that the vaccine was 100% effective in… Read More »
As October and National Breast Cancer Awareness month are quickly approaching, a new study by The University of Texas MD Anderson Cancer Center recently reported results from a gene therapy study that has shown to cause breast cancer cells to self-destruct, to lower the chance of recurrence, and to help increase the… Read More »
In gene therapy, viral vectors are the most common method used to deliver DNA into cells. Some attempts have been made to develop non-viral vectors (i.e. polyethylenimine (PEI)), but the gene transfer efficiency has not been as effective as viral vectors. Recently, a research team at the University of Bayreuth has succeeded… Read More »
A study published by Nature Structural & Molecular Biology describes how gamers using an online gaming framework called Foldit, deciphered the structure of a key protein, retroviral protease, that plays a critical role in the way HIV multiplies. Since the game was developed by reserachers at the University of Washington and debuted… Read More »
Choosing the right CMO for your clinical program is one of the most critical decisions you will make. Not only must your CMO be able to manufacture your product correctly, they must also be able to do it on-time and on-budget. But how do you evaluate a company that you’ve never worked… Read More »
A 20 year study funded by the Alliance for Cancer Gene Therapy, has released information about a new treatment that utilizes HIV to combat cancer. The trial that was developed from the University of Pennsylvania’s Abramson Cancer Center and Perelman School of Medicine uses a strain of the human immunodeficiency virus (HIV)… Read More »
Recent studies indicate that use “natural medicines” to treat diseases such as Cancer and Alzheimers from plants, animals, insects and microorganisms are gaining attention as results from several studies performed around the world are yielding promising results. One of the most interesting and recent studies using natural medicine uses a compound called… Read More »