VGXI 2017 ASGCT Poster

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“Novel Method for RNA Quantification and Exclusion from Plasmid DNA Vector Purification Process Stream”

Rapid quantification of RNA impurity levels present in process intermediates is challenging due to the absorbance of both RNA and DNA molecules at A260. VGXI has developed a rapid RNA quantification method by nephelometric turbidity measurement upon selective precipitation (salting-out) of RNA from process intermediates.

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