Second Generation DNA Vaccines and Delivery Methods

Second Generation DNA Vaccines DNA vaccines have come a long way resulting in a second generation of vast improvements bringing a surge of interest to the community. In both small and large animal models, second-generation DNA vaccines show that they assist cellular and humoral immune responses. Additionally, research suggests that newer DNA vaccines can more […]

Vaccines Have Been Known to Prevent Disease, What if they could Treat Disease?

Traditional vaccines are designed to prevent disease; researchers are working on something new: therapeutic vaccines, vaccinations that treat a disease after you have it. Currently, vaccine research is underway to use therapeutic vaccines to medically treat diseases such as: HIV, Herpes, Alzheimer’s disease and cancer Standard preventative vaccines work by helping your immune system develop […]

[BLOG] Dengue Fever 101

Since it became a global issue during World War II, researchers and scientists have been struggling to develop a vaccine for Dengue fever.  To date, there has been no success in eradicating this disease.  Before we get to the specifics of the challenges this disease presents, let’s cover the symptoms related to this tropical disease. […]

DNA Vaccine for Malaria Demonstrates Ability to Kill Infected Cells

A new potential vaccine for malaria is gaining media attention after successful pre-clinical trials in small animals and non-human primates.  Until now, the most effective malaria vaccine in human clinical trials has been GSK’s RTS,S vaccine.  Their vaccine demonstrated a 50% efficacy in children between the ages of 5 and 17 months and only a 30% […]

Brazilian DNA Vaccine for AIDS to be Tested in Rhesus Monkeys

In development since 2001, the HIVBr18 DNA vaccine developed at the Medical School at the University of Sao Paulo (USP) in Brazil may prevent transmission of human immunodeficiency virus (HIV) and development of acquired immune deficiency syndrome (AIDS). The DNA Vaccine encodes 18 conserved multiple HLA-DR-binding HIV-1 CD4 epitopes capable of eliciting broad CD4(+) T […]