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DNA Vaccine for Malaria Demonstrates Ability to Kill Infected Cells

A new potential vaccine for malaria is gaining media attention after successful pre-clinical trials in small animals and non-human primates.  Until now, the most effective malaria vaccine in human clinical trials has been GSK’s RTS,S vaccine.  Their vaccine demonstrated a 50% efficacy in children between the ages of 5 and 17 months and only a 30% […]

Brazilian DNA Vaccine for AIDS to be Tested in Rhesus Monkeys

In development since 2001, the HIVBr18 DNA vaccine developed at the Medical School at the University of Sao Paulo (USP) in Brazil may prevent transmission of human immunodeficiency virus (HIV) and development of acquired immune deficiency syndrome (AIDS). The DNA Vaccine encodes 18 conserved multiple HLA-DR-binding HIV-1 CD4 epitopes capable of eliciting broad CD4(+) T […]

Combination Cell & Gene Therapy for Brain Metastases of Breast Cancer

New research out of the UCLA Jonsson Comprehensive Cancer Center (JCCC) led by Carol Kruse, professor of neurosurgery, combined two therapies currently undergoing individual clinical trials to determine if the two used in tandem could demonstrate a greater efficacy and reduction of tumor size than either therapy alone. Dr. Kruse’s combination therapy includes both a […]

What Makes VGXI the Best Contract Manufacturing Organization?

VGXI was awarded the Vaccine Industry Excellence (ViE) Award for Best Contract Manufacturing Organization at the 6th Annual ViE Awards Ceremony held at the World Vaccine Congress on April 17th, 2013 in Washington, D.C. To read the full Press Release – click here. The following five categories illustrate what makes VGXI the Best Contract Manufacturing Organization […]

Cell Line Optimization for DNA Vaccine Production

“Therapeutic plasmid DNA vector” is promising technology for the future of gene therapy. Though still in the clinical trial stage, DNA vaccines have great potential of being successful as effective vaccination technology with negligible side effects. One of the most important considerations in designing a successful DNA vaccine production process is the selection of an […]